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KMID : 0648620090140020098
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Korean Journal of Nosocomial Infection Control
2009 Volume.14 No. 2 p.98 ~ p.102
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Seroprevalence of Hepatitis A Virus Antibody and Vaccination among Healthcare Workers in a Teaching Hospital
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Jeong Hye-Ran
Kim Bong-Hee
Kim Hyo-Youl
Kim Young-Keun
Uh Young
Jin Hei-Kyung
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Abstract
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Background: Recently, the incidence of hepatitis A virus (HAV) infection has been increasing in Korea, and an outbreak among healthcare workers (HCWs) has also been reported. This study aims to evaluate the seroepidemiology of hepatitis A among HCWs at an 820-bed teaching hospital in Korea, thereby facilitating HAV vaccination for these HCWs.
Methods: In June 2009, we assessed the total immunoglobulins against the HAV in the serum samples of 907 HCWs by using VIDAS Anti-HAV Total (bioMerieux, France).
Results: Seropositivity for HAV significantly increased with age (P＜0.001): 0% for ≤25 years, 9.4% for 26-30 years, 39.5% for 31-35 years, 66.7% for 36-40 years, 85.7% for 41-45 years, 96.0% for 46-50 years, 98.3% for 51-55 years, 95.8% for 56-60 years, and 100% for ≥61 years.
Conclusion: Since HCWs aged 20-40 years show low seropositivity for HAV vaccination against hepatitis A should be considered in all these HCWs.
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KEYWORD
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Hepatitis A virus, Healthcare workers, Seroprevalence, Vaccination, Hepatitis A antibodies
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